Welcome to PathFX

PathFX is designed to look at the pathways-level effects (pathway "FX") of a drug intervention. Under the hood, PathFX is an interaction-network tool that searches for the most relevant protein-protein interactions around a drug's target(s), and then analyzes for which phenotypes the network is enriched relative to the entire interaction network. The algorithm and the web application provide tabular results of associated phenotypes, and a summary figure and table of phenotype clusters based on semantic similarity between phenotypes.

This PathFX web application has been tested to work using the Google Chrome browser.

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To try our live examples, please register

You can download a pre-computed example for Metformin (10kB)

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